Screening for prostatakreft i Norge
DOI:
https://doi.org/10.5324/nje.v11i2.549Sammendrag
ENGLISH SUMMARY
Fosså SD, Høisæter PÅ.
Screening for prostate cancer in Norway. Nor J Epidemiol 2001; 11 (2): 147-152.
Background
Results
Conclusion
. Population-based PSA screening can not be recommended in Norway. PSA-based opportunistic
screening should be substantially reduced. If an asymptomatic man persistently requires PSA
testing, the responsible doctor has to inform him about the potential disadvantages as well as the potential
benefits associated with opportunistic screening, diagnosis and treatment of prostate cancer. PSAscreening
should be considered as a public health care strategy, depending on the results of the ERPCS.
. The rate of opportunistic screening in Norway in elderly men was about 7% in 1999 but isincreasing, with significant differences between the counties. The current health care strategy is to limit
opportunistic screening to a minimum, as the effectiveness of this task is unproven. Reduction of mortality
can only be achieved by the early diagnosis and treatment of “clinically important” prostate
cancer. The identification of these cases remains problematic in clinical routine. Data from the Cancer
Registry of Norway, and knowledge about prostate cancer tumour biology and epidemiology leave
doubt whether the aim of the ERPCS can be reached in 2008: The Norwegian Urological Cancer Group
has therefore not recommended Norway's participation in the ERPCS.
. PSA-based opportunistic screening for prostate cancer is increasing throughout theworld, and also in Norway. The mortality reducing effectiveness of population-based PSA screening
has, however, so far not been proven and it is currently addressed by a European randomised trial
(ERPCS). This trial aims to demonstrate a 20% reduction of the prostate cancer-related mortality rate in
the year 2008 in men who have had regular PSA analysis and, if possible, curatively intended treatment
of a newly diagnosed prostate cancer.
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