Brukermønster for østrogen i og etter overgangsalderen i Norge
DOI:
https://doi.org/10.5324/nje.v11i1.539Abstract
SAMMENDRAG
Bakgrunn:
Materiale og metode:
Resultater:
Konklusjon:
Prevalence of Hormone Replacement Therapy (HRT) in Norwegian women 45-64
years old: User characteristics and choices of therapy. The Norwegian Women and Cancer Study
(NOWAC) 1996-97.
Nor J Epidemiol 2001; 11 (1): 81-90.
ENGLISH SUMMARY
Background and objectives:
Material and methods:
Results:
Conclusion:
Our results suggest that user patterns are rapidly changing in Norway, and HRT has become a choice
for many women. More than four out of ten women reported ever use of systemic or local HRT, and one out of
three reported current use. Socio-economic differences between users and non-users seem to disappear in women
under 55 years of age, but persist in the older age groups. Short time use still dominates, but perhaps not for so
much longer.
Current use of systemic HRT was reported by 27.3% of the women while 38.0% reported ever use. Thehighest prevalence was in the age group 55-59 years where 35.6% were current users. More than 60% of the
women were classified as postmenopausal, two thirds of them naturally postmenopausal. Mean duration of
treatment was found to be approximately two years among earlier users but had increased to 4.5 years among
current users. Still the majority of women has not been using HRT beyond five years. Prevalence of use was
higher among earlier OC users, smokers, lean women and in households with high income. Among older women,
users had higher education than non-users, while this difference disappeared in the youngest women. Fixed
combinations of estradiol and noretisteroneacetate either cyclic or continuous, are used by six out of ten users.
A random sample of 18,199 Norwegian women aged 45-64 years responded to a postalquestionnaire in 1996-97. The questionnaire included questions about menstruation status and fertility, oral
contraceptives (OC) and HRT use, lifestyle, health and socioeconomic variables. The response rate was 60%.
There has been a considerable increase in the sale of non-contraceptive estrogens inNorway during the last ten years. We wanted to assess the prevalence of HRT in Norwegian women 45-64 years
and examine factors related to use.
Vi finner at brukerprevalens økte med 4% fra 1996 til 1997, og bruksmønster for østrogen rundtovergangsalderen synes å endres i nye generasjoner av brukere. Tre av ti kvinner i aktuell alder bruker systemisk
behandling med slike midler i dag. Det kan se ut til at sosioøkonomiske faktorers betydning for bruk minsker,
mens behandlingslengden øker.
Bakken K, Eggen AE.
Systemisk behandling gir 27,3% nåværende brukere, mens hele 38,0% har brukt slik midler noen
gang. Gjennomsnittlig brukstid varierer fra ca. 2 år hos tidligere brukere til ca. 4,5 år hos de som bruker nå.
Brukere ser ut til å være slankere og ha høyere husholdsinntekt enn ikke-brukere, i tillegg til at de oftere har brukt
p-piller og røkt. Blant de eldste kvinnene er brukere også karakterisert ved høyere utdannelsesnivå.
”Kvinner og kreft” er en prospektiv populasjonsstudie basert på utsendte spørreskjema til ettilfeldig utvalg av norske kvinner mellom 30-70 år. Undersøkelsen har pågått siden 1992, og mer enn 100 000
kvinner har bidratt med svar. Artikkelen er basert på data fra et utvalg på 18 199 kvinner i alderen 45-64 år som
besvarte spørreskjema utsendt i 1996-97. Svarprosenten var 60%.
Salgstall for østrogenholdige preparater knyttet til overgangsalderen er firedoblet i løpet av de siste 10år. Østrogens rolle i forebyggende behandling av kroniske sykdommer i alderdommen, for eksempel hjertekarsykdom
og osteoporose, fokuseres stadig mer. Artikkelen presenterer prevalenstall for bruk, brukerkarakteristika
og varighet av behandlingen.
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