Arbeidsmiljø og røyking som årsak til lungekreft: noen epidemiologiske betraktninger
DOI:
https://doi.org/10.5324/nje.v5i2.257Abstract
SAMMENDRAG
Lungekreft er en av de hyppigst forekommende og alvorligste kreftsykdommene i verden. Etter den
voldsomme økningen i sigarettforbruket i første halvdel av dette århundret har røykevanene inntatt
en dominerende plass blant årsakene til lungekreft, mens yrkeseksponeringer er regnet for å være
den nest viktigste årsak. Lungekreft er den vanligste yrkesbetingete kreftsykdom i Norge. Røykevanene
er en potensiell confounder i vurderingen av yrkesmessige årsaker til lungekreft, men både
teoretiske betraktninger og gjennomførte studier tyder på at problemet er relativt lite. Samvirkning
mellom røykevaner og yrkeseksponering er best beskrevet når det gjelder asbeststøv og radon, og ser
ut til å følge et multiplikativt mønster. For andre eksponeringer er forholdet mer ufullstendig belyst.
Andelen lungekrefttilfeller som tilskrives yrkeseksponering, kan være betydelig i yrkesgrupper eller
geografiske områder hvor kreftfremkallende stoffer har vært i utstrakt bruk.
Grimsrud TK.
Occupational exposures and smoking as causes of lung cancer: Some
epidemiological considerations.
Nor J Epidemiol 1995; 5 (2): 121-127.
ENGLISH SUMMARY
Lung cancer is one of the the most common and most serious cancer diseases in the world. The
enormous increase in cigarette consumption during the first half of this century made smoking the
dominating cause of lung cancer. Occupational exposures are considered to be the second most
important cause. Lung cancer is the most frequent occupational cancer in Norway. Smoking is a
potential confounder in the study of occupational lung cancer. Theoretical and empirical considerations
do however indicate that the problem is of minor magnitude. Interaction between smoking
and occupational exposures is described for asbestos and radon and appears to follow a multiplicative
pattern. Interaction with other occupational exposures is less well studied. The proportion of
lung cancer cases attributable to occupational factors can be significant in certain occupations and
geographical regions.
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