Matteo Sangermani
Om
Matteo Sangermani has a PhD in Biophysics (University of Basel) and is working as a Postdoc Fellow at the MR Cancer (ISB) in the group of Guro F. Giskeødegård. He is part of a large clinical study on breast cancer and his research focuses on the gut microbiome. He investigates how changes in the gut microbiome influence the recovery of breast cancer patients and post-treatment quality of life. In the wetlab he is employing 16S rRNA amplicon sequencing, metatranscriptomics and NMR metabolomics; in silico he uses Python and R to analyse raw sequencing data, and then perform multivariate data analysis on these multi-omic datasets to draw conclusions. The research goal is to gain insights on how and to which degree changes at one level (e.g. composition) correlates with changes at another levels of the microbiome activity (e.g. gene expression or metabolites), and explore how changes (over time, within and between individuals) correlates with treatment of cancer.
Journal Pubblications: see full list on ORCID
Sangermani M; Hug I; Sauter N; Pfohl T and Jenal U - (2019) - Tad pili play a dynamic role in Caulobacter crescentus surface colonization. - MBio, 10(3). - doi: 10.1128/mBio.01237-19 |
Laventie BJ ; Sangermani M; et al. - (2019) - A surface-induced asymmetric program promotes tissue colonization by Pseudomonas aeruginosa. - Cell Host Microbe, 25(1) - doi: 10.1016/j.chom.2018.11.008 |
Rossmann F; Hug I; Sangermani M; Jenal U and Beeby M - (2020) - In situ structure of the Caulobacter crescentus flagellar motor and visualization of binding of a CheY-homolog. - Molecular Microbiology 114:443–453. - doi: 10.1111/mmi.14525 |
Sprecher KS; Hug I; Nesper J; Potthoff E; Mahi MA; Sangermani M; Kaever V; Schwede T; Vorholt J; Jenal U. (2017) - Cohesive properties of the Caulobacter crescentus holdfast adhesin are regulated by a novel c-di-GMP effector protein. - MBio, 8(2). - doi: 10.1128/mBio.00294-17 |
Debik J; Sangermani M; Wang F; Madssen TF; Giskeødegård GF - (2021) - Multivariate analysis of NMR-based metabolomic data. - NMR in Biomedicine - doi: 10.1002/nbm.4638 |
Grant: (ongoing) Postdoc.Mobility 2020, from Swiss National Fundation (P400PM_194492)
Kompetanseord
Forskning
Publikasjoner
2024
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Sangermani, Matteo;
Desiati, Indri;
Jørgensen, Solveig Maria;
Li, Jia V.;
Andreassen, Trygve;
Bathen, Tone Frost.
(2024)
Stability in fecal metabolites amid a diverse gut microbiome composition: a one-month longitudinal study of variability in healthy individuals.
Gut microbes
Vitenskapelig artikkel
2022
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Giskeødegård, Guro F.;
Madssen, Torfinn Støve;
Sangermani, Matteo;
Lundgren, Steinar;
Wethal, Torgeir;
Andreassen, Trygve.
(2022)
Longitudinal Changes in Circulating Metabolites and Lipoproteins After Breast Cancer Treatment.
Frontiers in Oncology
Vitenskapelig artikkel
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Sauter, Nora;
Sangermani, Matteo;
Hug, Isabelle;
Jenal, Urs;
Pfohl, Thomas.
(2022)
Bacteria-on-a-bead: probing the hydrodynamic interplay of dynamic cell appendages during cell separation.
Communications Biology
Vitenskapelig artikkel
Tidsskriftspublikasjoner
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Sangermani, Matteo;
Desiati, Indri;
Jørgensen, Solveig Maria;
Li, Jia V.;
Andreassen, Trygve;
Bathen, Tone Frost.
(2024)
Stability in fecal metabolites amid a diverse gut microbiome composition: a one-month longitudinal study of variability in healthy individuals.
Gut microbes
Vitenskapelig artikkel
-
Giskeødegård, Guro F.;
Madssen, Torfinn Støve;
Sangermani, Matteo;
Lundgren, Steinar;
Wethal, Torgeir;
Andreassen, Trygve.
(2022)
Longitudinal Changes in Circulating Metabolites and Lipoproteins After Breast Cancer Treatment.
Frontiers in Oncology
Vitenskapelig artikkel
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Sauter, Nora;
Sangermani, Matteo;
Hug, Isabelle;
Jenal, Urs;
Pfohl, Thomas.
(2022)
Bacteria-on-a-bead: probing the hydrodynamic interplay of dynamic cell appendages during cell separation.
Communications Biology
Vitenskapelig artikkel
Formidling
2024
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PosterDesiati, Indri; Bathen, Tone Frost; Giskeødegård, Guro F.; Sangermani, Matteo. (2024) Effect of Repeated Freeze-Thaw Cycles on Fecal-Microbiome Profile. National network of breast cancer research Nasjonalt Nettverk for Brystkreftforskning Nettverksmøte , Tromsø 2024-03-09 - 2024-03-11
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PosterQuattrini, Nicole; Sangermani, Matteo; Tessem, May-Britt; Hveem, Kristian; Giskeødegård, Guro F.. (2024) Identifying Gut Microbiome Signatures of Cancer Development. Digital Life Norway Research School , Oslo 2024-10-14 - 2024-10-16
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PosterQuattrini, Nicole; Giampà , Marco; Ghesquière, Barth; Giskeødegård, Guro F.; Sangermani, Matteo. (2024) Human faecal metabolite analysis from two different sampling techniques using DESI-MS. 2024 Metabolomics Conference , Osaka 2024-06-15 - 2024-06-21
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Vitenskapelig foredragSangermani, Matteo. (2024) Do’s and don’ts in gut microbiome analysis Annual Workshop on Breast Cancer Research Organized by National Network for Breast Cancer Research Scandic Stavanger City, March 19-20, 2024. National Network for Breast Cancer Research Annual Workshop on Breast Cancer Research , Stavanger 2024-03-19 - 2024-03-20
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Faglig foredragSangermani, Matteo; Abhibhav, Sharma. (2024) Navigating Academic Life. Digital Life Norway Digital Life Norway research school , Trondheim 2024-04-09 - 2024-05-24
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Populærvitenskapelig foredragQuattrini, Nicole; Sangermani, Matteo; Giskeødegård, Guro F.. (2024) Gut Microbiome Signatures of Cancer Development . NTNU Helse NTNU Health and Life Science Seminar , Trondheim 2024-12-02 - 2024-12-02
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PosterSangermani, Matteo. (2024) Comparison between two fecal collection approaches for untargeted metabolomics using NMR and LC-MS. Internetional Metabolomics Society Metabolomics 2024 , Osaka 2024-06-14 - 2024-06-20
2023
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PosterDesiati, Indri; Bathen, Tone Frost; Giskeødegård, Guro F.; Sangermani, Matteo. (2023) Unraveling the gut microbiome: A metagenomic longitudinal study on composition, diversity, and dynamics. Nordic metabolomic society 3rd Nordic Metabolomics Conferance , Trondheim 2023-10-18 - 2023-10-20
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PosterSangermani, Matteo; Desiati, Indri; Bathen, Tone Frost; Giskeødegård, Guro F.. (2023) Effect of longitudinal sampling in gut microbiome. Nordic Metabolomics Society 2nd Nordic Metabolomics Conference , Copenhagen 2023-09-06 - 2024-09-09
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PosterSangermani, Matteo; Desiati, Indri; Jorgensen, Solveig; Bathen, Tone Frost; Giskeødegård, Guro F.. (2023) Correlating human gut microbiota metabolites and composition in a longitudinal study. Nordic Metabolomics Society 3rd Nordic Metabolomics Conference , Trondheim 2023-10-18 - 2023-10-20
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Faglig foredragSangermani, Matteo. (2023) Correlating human gut microbiota metabolites and composition in a longitudinal study. International Metabolomics Society Metabolomics 2023 , Niagara 2023-06-18 - 2023-06-22
2022
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Vitenskapelig foredragGiskeødegård, Guro F.; Madssen, Torfinn Støve; Sangermani, Matteo; Lundgren, Steinar; Wethal, Torgeir; Andreassen, Trygve. (2022) Longitudinal modelling reveals distinct changes in circulating metabolites and lipoprotein subfractions after breast cancer treatment. The Metabolomics Society 18th International Conference of the Metabolomics Society, , Valencia 2022-06-19 - 2022-06-23
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Faglig foredragSangermani, Matteo; Doshmanziari, Roya. (2022) Navigating Academic Life 2022. Digital Life Norway Digital Life Norway Research School , Stavanger 2022-09-01 - 2022-09-02
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Populærvitenskapelig foredrag
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PosterSangermani, Matteo; Desiati, Indri; Bathen, Tone Frost; Giskeødegård, Guro F.. (2022) Effect of longitudinal sampling in gut microbiome. Metabolomics 2022 , Valencia 2022-06-19 - 2022-06-23