Matteo Sangermani
Om
Matteo Sangermani has a PhD in Biophysics (University of Basel) and is working as a Postdoc Fellow at the MR Cancer (ISB) in the group of Guro F. Giskeødegård. He is part of a large clinical study on breast cancer and his research focuses on the gut microbiome. He investigates how changes in the gut microbiome influence the recovery of breast cancer patients and post-treatment quality of life. In the wetlab he is employing 16S rRNA amplicon sequencing, metatranscriptomics and NMR metabolomics; in silico he uses Python and R to analyse raw sequencing data, and then perform multivariate data analysis on these multi-omic datasets to draw conclusions. The research goal is to gain insights on how and to which degree changes at one level (e.g. composition) correlates with changes at another levels of the microbiome activity (e.g. gene expression or metabolites), and explore how changes (over time, within and between individuals) correlates with treatment of cancer.
Journal Pubblications: see full list on ORCID
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Sangermani M; Hug I; Sauter N; Pfohl T and Jenal U - (2019) - Tad pili play a dynamic role in Caulobacter crescentus surface colonization. - MBio, 10(3). - doi: 10.1128/mBio.01237-19 |
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Laventie BJ ; Sangermani M; et al. - (2019) - A surface-induced asymmetric program promotes tissue colonization by Pseudomonas aeruginosa. - Cell Host Microbe, 25(1) - doi: 10.1016/j.chom.2018.11.008 |
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Rossmann F; Hug I; Sangermani M; Jenal U and Beeby M - (2020) - In situ structure of the Caulobacter crescentus flagellar motor and visualization of binding of a CheY-homolog. - Molecular Microbiology 114:443–453. - doi: 10.1111/mmi.14525 |
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Sprecher KS; Hug I; Nesper J; Potthoff E; Mahi MA; Sangermani M; Kaever V; Schwede T; Vorholt J; Jenal U. (2017) - Cohesive properties of the Caulobacter crescentus holdfast adhesin are regulated by a novel c-di-GMP effector protein. - MBio, 8(2). - doi: 10.1128/mBio.00294-17 |
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Debik J; Sangermani M; Wang F; Madssen TF; Giskeødegård GF - (2021) - Multivariate analysis of NMR-based metabolomic data. - NMR in Biomedicine - doi: 10.1002/nbm.4638 |
Grant: (ongoing) Postdoc.Mobility 2020, from Swiss National Fundation (P400PM_194492)
Kompetanseord
Forskning
Publikasjoner
2024
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Sangermani, Matteo;
Desiati, Indri;
Jørgensen, Solveig M.;
Li, Jia V.;
Andreassen, Trygve;
Bathen, Tone Frost.
(2024)
Stability in fecal metabolites amid a diverse gut microbiome composition: a one-month longitudinal study of variability in healthy individuals.
Gut microbes
Vitenskapelig artikkel
2022
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Giskeødegård, Guro F.;
Madssen, Torfinn Støve;
Sangermani, Matteo;
Lundgren, Steinar;
Wethal, Torgeir;
Andreassen, Trygve.
(2022)
Longitudinal Changes in Circulating Metabolites and Lipoproteins After Breast Cancer Treatment.
Frontiers in Oncology
Vitenskapelig artikkel
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Sauter, Nora;
Sangermani, Matteo;
Hug, Isabelle;
Jenal, Urs;
Pfohl, Thomas.
(2022)
Bacteria-on-a-bead: probing the hydrodynamic interplay of dynamic cell appendages during cell separation.
Communications Biology
Vitenskapelig artikkel
Tidsskriftspublikasjoner
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Sangermani, Matteo;
Desiati, Indri;
Jørgensen, Solveig M.;
Li, Jia V.;
Andreassen, Trygve;
Bathen, Tone Frost.
(2024)
Stability in fecal metabolites amid a diverse gut microbiome composition: a one-month longitudinal study of variability in healthy individuals.
Gut microbes
Vitenskapelig artikkel
-
Giskeødegård, Guro F.;
Madssen, Torfinn Støve;
Sangermani, Matteo;
Lundgren, Steinar;
Wethal, Torgeir;
Andreassen, Trygve.
(2022)
Longitudinal Changes in Circulating Metabolites and Lipoproteins After Breast Cancer Treatment.
Frontiers in Oncology
Vitenskapelig artikkel
-
Sauter, Nora;
Sangermani, Matteo;
Hug, Isabelle;
Jenal, Urs;
Pfohl, Thomas.
(2022)
Bacteria-on-a-bead: probing the hydrodynamic interplay of dynamic cell appendages during cell separation.
Communications Biology
Vitenskapelig artikkel
Formidling
2024
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PosterDesiati, Indri; Bathen, Tone Frost; Giskeødegård, Guro F.; Sangermani, Matteo. (2024) Effect of Repeated Freeze-Thaw Cycles on Fecal-Microbiome Profile. National network of breast cancer research Nasjonalt Nettverk for Brystkreftforskning Nettverksmøte , Tromsø 2024-03-09 - 2024-03-11
2023
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PosterDesiati, Indri; Bathen, Tone Frost; Giskeødegård, Guro F.; Sangermani, Matteo. (2023) Unraveling the gut microbiome: A metagenomic longitudinal study on composition, diversity, and dynamics. Nordic metabolomic society 3rd Nordic Metabolomics Conferance , Trondheim 2023-10-18 - 2023-10-20
2022
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Vitenskapelig foredragGiskeødegård, Guro F.; Madssen, Torfinn Støve; Sangermani, Matteo; Lundgren, Steinar; Wethal, Torgeir; Andreassen, Trygve. (2022) Longitudinal modelling reveals distinct changes in circulating metabolites and lipoprotein subfractions after breast cancer treatment. The Metabolomics Society 18th International Conference of the Metabolomics Society, , Valencia 2022-06-19 - 2022-06-23