Oluf Dimitri Røe

Om

Undertegnede er overlege i onkologi ved Kreftpoliklinikken, Sykehuset Levanger, Kirurgisk Avdeling og professor ved NTNU.

Hovedprosjekt: Cancer-Biomarkers in HUNT, kort innføring
I denne internasjonale multidisiplinære studien er målet å oppdage signal-molekyler i blod for tidlig diagnostikk av lungekreft og mesotheliom.

Lungekreft og mesotheliom (kreft i bryst- eller bukhinne) er sykdommer som i høy grad skyldes inhalasjon av tobakksrøyk og/eller asbest og er meget vanskelige å behandle når de først gir symptomer. Gjennomsnittlig fem-års overlevelse for lungekreft er bare 15% og 0-5% for mesotheliom. Lungekreft er den kreftsykdommen som i dag tar flest liv globalt. Asbest- og tobakksrelatert kreft er økende de fleste steder i verden og vil øke i årene som kommer da bruken av asbest og tobakk på verdensbasis fortsatt er stor. For å kunne endre forløpet på disse sykdommene er tidlig diagnostikk av avgjørende betydning og slike markører mangler. Derfor er oppdagelsen av nye biomarkører for tidlig diagnostikk i blod/serum svært viktig.

MicroRNA er molekyler som regulerer gen-uttrykket via mRNA. Hos mennesket har man hittil påvist ca 2500 ulike microRNA og funnet at de er overraskende stabile i serum. I dag er det allerede påvist mange lovende microRNA kandidat-markører for ulike kreftsykdommer. For lungekreft og mesotheliom er det ikke publisert noen større studie med pre-kliniske blodprøver der alle kjente microRNA er undersøkt.

I dette arbeidet vil vi sammenlikne micoRNA-profilene med proteiner og metabolitter i blod/serum tatt 1-5 år før fra de som fikk kreft mot de som ikke fikk kreft og derved forhåpentligvis oppdage nye relevante tidlig-markører.

Meso-Lung HUNT er et internasjonalt tre-delt prosjekt som vil gå over flere år og som involverer nasjonale og internasjonale samarbeidspartnere ved Universiteter i Kina (Nanjing), Sverige (Uppsala), Hellas (Kreta) samt Aalborg (Danmark).

Status og plan videre
Cancer-Biomarker-HUNT: Samarbeidsorganet innvilget I 2014 5,7 mill. Nok og verdens lungekreftorganisasjon IASLC innvilget 2,6 mill. Nok til dette prosjektet. Dette samarbeids-prosjektet med den unike biobanken HUNT har vi nå identifisert alle de som fikk lungekreft og mesotheliom samt deres kontroller. Vi har i tillegg til mikroRNA begynt å analysere protein og metabolittprofil i serum ved ulike metoder. Preliminære resultater ble presentert bla i Cambridge og ved IMIG i Cape Town 2014 og nye resultater ved IMIG 2016, 2018, ASCO i Chicago i 2016, 2017, 2018, 2019, IASLC 2018, 2019.

I Nanjing, Kina har vi siden 2010 samarbeidet tett med kliniske og biologiske studier. Vi har sampublisert mange artikler på mesotheliom, magekreft og lungekreft.

Videre er det etablert et samarbeide med Aalborg Universitetshospital, Danmark, der vi har tilgang til en biobank med flere tusen lungekreft og mesotheliom-prøver.

Dette samarbeidet har ført til samforfatterskap ved mange artikler og abstracts og en PhD

Publikasjoner

2021

Ringgaard Petersen, Thomas; Panou, Vasiliki; Meristoudis, Christos; Weinreich, Ulla Møller; Røe, Oluf Dimitri. (2021) Clinical prognostic factors in pleural mesothelioma: best supportive care and anti-tumor treatments in a real-life setting. Acta Oncologica
Vitenskapelig artikkel
Szejniuk, Weronika Maria; Cekala, M.; Bøgsted, Martin; Meristoudis, Christos; McCulloch, Tine; Falkmer, Ursula. (2021) Adjuvant platinum-based chemotherapy in non-small cell lung cancer: The role of relative dose-intensity and treatment delay. Cancer Treatment and Research Communications
Vitenskapelig artikkel

2020

Nguyen, Olav Toai Duc; Sundstrøm, Stein Harald; Westvik, Ganna Surzhykova; Røttereng, Ane Karoline Stræte; Melhus, Mona Røli; Bergseth, Cecilie. (2020) Major durable response of pembrolizumab in chemotherapy refractory small cell bladder cancer: A case report. Case Reports in Oncology
Vitenskapelig artikkel
Würtz, Else Toft; Hansen, Johnni; Røe, Oluf Dimitri; Omland, Øyvind. (2020) Asbestos exposure and haematological malignancies: a Danish cohort study. European Journal of Epidemiology (EJE)
Vitenskapelig artikkel
Panou, Vasiliki; Røe, Oluf Dimitri. (2020) Inherited Genetic Mutations and Polymorphisms in Malignant Mesothelioma: A Comprehensive Review. International Journal of Molecular Sciences
Vitenskapelig oversiktsartikkel/review
Røe, Oluf Dimitri. (2020) Democratic and ethical problem of lung cancer screening: Exclusion of true high-risk populations. Can it be fixed? Yes. BMJ Open Respiratory Research
Vitenskapelig oversiktsartikkel/review

2019

Panou, Vasiliki; Vyberg, Mogens; Meristoudis, Christos; Hansen, Johnni; Bøgsted, Martin; Omland, Øyvind. (2019) Non-occupational exposure to asbestos is the main cause of malignant mesothelioma in women in North Jutland, Denmark. Scandinavian Journal of Work, Environment and Health
Vitenskapelig artikkel
Lakiotaki, Kleanthi; Georgakopoulos, George; Castanas, Elias; Røe, Oluf Dimitri; Borboudakis, Giorgos; Tsamardinos, Ioannis. (2019) A data driven approach reveals disease similarity on a molecular level. npj Systems Biology and Applications
Vitenskapelig artikkel
Dalsgaard, Sofie Bunemann; Würtz, Else Toft; Hansen, Johnni; Røe, Oluf Dimitri; Omland, Øyvind. (2019) Environmental asbestos exposure in childhood and risk of mesothelioma later in life: A long-term follow-up register-based cohort study. Occupational and Environmental Medicine
Vitenskapelig artikkel
Røe, Oluf Dimitri; Markaki, Maria; Tsamardinos, Ioannis; Lagani, Vincenzo; Nguyen, Olav Toai Duc; Pedersen, Jesper Holst. (2019) ‘Reduced’ HUNT model outperforms NLST and NELSON study criteria in predicting lung cancer in the Danish screening trial . BMJ Open Respiratory Research
Vitenskapelig artikkel
Szejniuk, Weronika Maria; Nielsen, Martin Skovmos; Brønnum, Dorthe; Takacs-Szabo, Z; Weinreich, Ulla Møller; Pilegaard Thomsen, L. (2019) Fractional exhaled nitric oxide as a potential biomarker for radiation pneumonitis in patients with non-small cell lung cancer: A pilot study. Clinical and Translational Radiation Oncology
Vitenskapelig artikkel

2018

Szejniuk, Weronika Maria; Robles, Ana I.; McCulloch, Tine; Falkmer, Ursula; Røe, Oluf Dimitri. (2018) Epigenetic predictive biomarkers for response or outcome to platinum-based chemotherapy in non-small cell lung cancer, current state-of-art. The Pharmacogenomics Journal
Vitenskapelig artikkel
Panou, Vasiliki; Gadiraju, Meghana; Wolin, Arthur; Weipert, Caroline M.; Skarda, Emily; Husain, Aliya N.. (2018) Frequency of germline mutations in cancer susceptibility genes in malignant mesothelioma. Journal of Clinical Oncology
Vitenskapelig artikkel
Rangul, Vegar; Sund, Erik Reidar; Mork, Paul Jarle; Røe, Oluf Dimitri; Bauman, Adrian. (2018) The associations of sitting time and physical activity on total and site-specific cancer incidence: Results from the HUNT study, Norway. PLOS ONE
Vitenskapelig artikkel
Røe, Oluf Dimitri. (2018) Mesothelioma diagnosis and prognosis, are we moving beyond histology and performance status towards circulating biomarkers?. Journal of Thoracic Disease (JTD)
Leder
Markaki, Maria Dorothea Haaberg; Tsamardinos, Ioannis; Langhammer, Arnulf; Lagani, Vincenzo; Hveem, Kristian; Røe, Oluf Dimitri. (2018) A Validated Clinical Risk Prediction Model for Lung Cancer in Smokers of All Ages and Exposure Types: A HUNT Study. EBioMedicine
Vitenskapelig artikkel

2017

Wang, Q; Chen, Q; Zhu, L; Chen, M; Xu, W; Panday, S. (2017) JWA regulates TRAIL-induced apoptosis via MARCH8-mediated DR4 ubiquitination in cisplatin-resistant gastric cancer cells. Oncogenesis
Vitenskapelig artikkel
Røe, Oluf Dimitri. (2017) The High Cost of New Cancer Therapies-A Challenge of Inequality for All Countries. JAMA Oncology
Short communication
Røe, Oluf Dimitri; Wahl, Sissel Gyrid Freim. (2017) The undifferentiated carcinoma that became a melanoma: Re-biopsy of a cancer of an unknown primary site: a case report. Journal of Medical Case Reports
Vitenskapelig artikkel

2016

Li, Qiang; Zhi, Xiaofei; Zhou, Jianping; Tao, Ran; Zhang, Jiaxuan; Chen, Peisheng. (2016) Circulating tumor cells as a prognostic and predictive marker in gastrointestinal stromal tumors: A prospective study. OncoTarget
Vitenskapelig artikkel
Qian, Jing; Zhu, Weiyou; Wang, Keming; Ma, Lin; Xu, Jin; Xu, Tongpeng. (2016) JWA loss promotes cell migration and cytoskeletal rearrangement by affecting HER2 expression and identifies a high-risk subgroup of HER2-positive gastric carcinoma patients. OncoTarget
Vitenskapelig artikkel
Zhi, Xiaofei; Jiang, Baofei; Yu, Junbo; Røe, Oluf Dimitri; Qin, Jun; Ni, Qingfeng. (2016) Prognostic role of microscopically positive margins for primary gastrointestinal stromal tumors: a systematic review and meta-analysis. Scientific Reports
Vitenskapelig artikkel
Chen, Xiao-Feng; Qian, Jing; Pei, Dong; Zhou, Chen; Røe, Oluf Dimitri; Zhu, Fang. (2016) Prognostic value of perioperative leukocyte count in resectable gastric cancer. World Journal of Gastroenterology (WJG)
Vitenskapelig artikkel
Robles, Ana I.; Olsen, Karina Standahl; Tsui, Dana W.T.; Georgoulias, Vassilis; Creaney, Jenette; Dobra, Katalin. (2016) Excerpts from the 1st international NTNU symposium on current and future clinical biomarkers of cancer: innovation and implementation, June 16th and 17th 2016, Trondheim, Norway. Journal of Translational Medicine
Vitenskapelig artikkel
Røe, Oluf Dimitri; Panou, V. (2016) Pemetrexed as first or second line in 112 danish patients. Journal of Clinical Oncology
Sammendrag/abstract
Røe, Oluf Dimitri; Mjelle, Robin; Sætrom, Pål; Andreassen, Trygve; Bathen, Tone Frost; Hveem, Kristian. (2016) Serum microRNAs/enriched pathways in lung cancer 1-4 years before diagnosis: A pilot study from the HUNT Biobank, Norway. Journal of Clinical Oncology
Sammendrag/abstract
Qian, Jing; Qian, Yingying; Wang, Jian; Gu, Bing; Pei, Dong; He, Shaohua. (2016) A clinical prognostic scoring system for resectable gastric cancer to predict survival and benefit from paclitaxel- or oxaliplatin-based adjuvant chemotherapy. Drug Design, Development and Therapy
Vitenskapelig artikkel

2015

Røe, Oluf Dimitri; Wyller, Torgeir Bruun. (2015) Hva står på spill med lokalsykehusene? :. Bioingeniøren
Leserinnlegg
Gao, Zhibin; Hiroshima, Kenzo; Wu, Xiaodong; Zhang, Jixian; Shao, Dichu; Shao, Huajiang. (2015) Asbestos textile production linked to malignant peritoneal and pleural mesothelioma in women: Analysis of 28 cases in Southeast China. American Journal of Industrial Medicine
Vitenskapelig artikkel
Zhu, Weiyou; Røe, Oluf Dimitri; Wu, Chen; Li, Wei; Guo, Renhua; Gu, Yanhong. (2015) Activity of pemetrexed-based regimen as first-line chemotherapy for advanced non-small cell lung cancer with asymptomatic inoperable brain metastasis: A retrospective study. Journal of chemotherapy
Vitenskapelig artikkel
Panou, V; Vyberg, M; Weinreich, UM; Meristoudis, C; Falkmer, UG; Røe, Oluf Dimitri. (2015) The established and future biomarkers of malignant pleural mesothelioma. Cancer Treatment Reviews
Vitenskapelig oversiktsartikkel/review
Røe, Oluf Dimitri; Stella, Giulia Maria. (2015) Malignant pleural mesothelioma: History, controversy and future of a manmade epidemic. European Respiratory Review
Vitenskapelig oversiktsartikkel/review

2010

Sandeck, Helmut; Røe, Oluf Dimitri; Kjærheim, Kristina; Willèn, Helena; Larsson, Erik. (2010) Re-evaluation of histological diagnoses of malignant mesothelioma by immunohistochemistry. Diagnostic Pathology
Vitenskapelig artikkel
Røe, Oluf Dimitri; Anderssen, Endre; Sandeck, Helmut; Christensen, Tone; Larsson, Erik; Lundgren, Steinar. (2010) Malignant pleural mesothelioma: Genome-wide expression patterns reflectinggeneral resistance mechanisms and a proposal of novel targets. Lung Cancer
Vitenskapelig artikkel
Kleppen, Dag Mattis; Pavlovic, Jovan; Fossen, Anne; Azziz, Idd; Røe, Oluf Dimitri; Haug, Christian. (2010) Bengalo : Foy.
Musikk - innspillingsprodukt

2009

Røe, Oluf Dimitri; Anderssen, Endre; Helge, Eli; Pettersen, Caroline Hild; Olsen, Karina Standahl; Sandeck, H. (2009) Genome-Wide Profile of Pleural Mesothelioma versus Parietal and Visceral Pleura: The emerging Gene Portrait of the Mesothelioma Phenotype. PLOS ONE
Vitenskapelig artikkel

2008

Røe, Oluf Dimitri; Creaney, J; Lundgren, Steinar; Larsson, Erik; Sandech, Helmut; Boffetta, P. (2008) Mesothelin-related Predictive and Prognostic Factors in Malignant Mesothelioma, a nested case-control study. Lung Cancer
Vitenskapelig artikkel
Røe, Oluf Dimitri. (2008) Malignant Mesothelioma:Virus, Biomarkers and Genes- a Translational Approach. NTNU/Oluf Dimitri Røe
Doktorgradsavhandling

2007

Kjaerheim, K; Røe, Oluf Dimitri; Waterboer, T; Sehr, P; Rizk, R; Dai, HY. (2007) Absence of SV40 antibodies or DNA fragments in prediagnostic mesothelioma serum samples. International Journal of Cancer
Vitenskapelig artikkel

Tidsskriftspublikasjoner

Ringgaard Petersen, Thomas; Panou, Vasiliki; Meristoudis, Christos; Weinreich, Ulla Møller; Røe, Oluf Dimitri. (2021) Clinical prognostic factors in pleural mesothelioma: best supportive care and anti-tumor treatments in a real-life setting. Acta Oncologica
Vitenskapelig artikkel
Szejniuk, Weronika Maria; Cekala, M.; Bøgsted, Martin; Meristoudis, Christos; McCulloch, Tine; Falkmer, Ursula. (2021) Adjuvant platinum-based chemotherapy in non-small cell lung cancer: The role of relative dose-intensity and treatment delay. Cancer Treatment and Research Communications
Vitenskapelig artikkel
Nguyen, Olav Toai Duc; Sundstrøm, Stein Harald; Westvik, Ganna Surzhykova; Røttereng, Ane Karoline Stræte; Melhus, Mona Røli; Bergseth, Cecilie. (2020) Major durable response of pembrolizumab in chemotherapy refractory small cell bladder cancer: A case report. Case Reports in Oncology
Vitenskapelig artikkel
Würtz, Else Toft; Hansen, Johnni; Røe, Oluf Dimitri; Omland, Øyvind. (2020) Asbestos exposure and haematological malignancies: a Danish cohort study. European Journal of Epidemiology (EJE)
Vitenskapelig artikkel
Panou, Vasiliki; Røe, Oluf Dimitri. (2020) Inherited Genetic Mutations and Polymorphisms in Malignant Mesothelioma: A Comprehensive Review. International Journal of Molecular Sciences
Vitenskapelig oversiktsartikkel/review
Røe, Oluf Dimitri. (2020) Democratic and ethical problem of lung cancer screening: Exclusion of true high-risk populations. Can it be fixed? Yes. BMJ Open Respiratory Research
Vitenskapelig oversiktsartikkel/review
Panou, Vasiliki; Vyberg, Mogens; Meristoudis, Christos; Hansen, Johnni; Bøgsted, Martin; Omland, Øyvind. (2019) Non-occupational exposure to asbestos is the main cause of malignant mesothelioma in women in North Jutland, Denmark. Scandinavian Journal of Work, Environment and Health
Vitenskapelig artikkel
Lakiotaki, Kleanthi; Georgakopoulos, George; Castanas, Elias; Røe, Oluf Dimitri; Borboudakis, Giorgos; Tsamardinos, Ioannis. (2019) A data driven approach reveals disease similarity on a molecular level. npj Systems Biology and Applications
Vitenskapelig artikkel
Dalsgaard, Sofie Bunemann; Würtz, Else Toft; Hansen, Johnni; Røe, Oluf Dimitri; Omland, Øyvind. (2019) Environmental asbestos exposure in childhood and risk of mesothelioma later in life: A long-term follow-up register-based cohort study. Occupational and Environmental Medicine
Vitenskapelig artikkel
Røe, Oluf Dimitri; Markaki, Maria; Tsamardinos, Ioannis; Lagani, Vincenzo; Nguyen, Olav Toai Duc; Pedersen, Jesper Holst. (2019) ‘Reduced’ HUNT model outperforms NLST and NELSON study criteria in predicting lung cancer in the Danish screening trial . BMJ Open Respiratory Research
Vitenskapelig artikkel
Szejniuk, Weronika Maria; Nielsen, Martin Skovmos; Brønnum, Dorthe; Takacs-Szabo, Z; Weinreich, Ulla Møller; Pilegaard Thomsen, L. (2019) Fractional exhaled nitric oxide as a potential biomarker for radiation pneumonitis in patients with non-small cell lung cancer: A pilot study. Clinical and Translational Radiation Oncology
Vitenskapelig artikkel
Szejniuk, Weronika Maria; Robles, Ana I.; McCulloch, Tine; Falkmer, Ursula; Røe, Oluf Dimitri. (2018) Epigenetic predictive biomarkers for response or outcome to platinum-based chemotherapy in non-small cell lung cancer, current state-of-art. The Pharmacogenomics Journal
Vitenskapelig artikkel
Panou, Vasiliki; Gadiraju, Meghana; Wolin, Arthur; Weipert, Caroline M.; Skarda, Emily; Husain, Aliya N.. (2018) Frequency of germline mutations in cancer susceptibility genes in malignant mesothelioma. Journal of Clinical Oncology
Vitenskapelig artikkel
Rangul, Vegar; Sund, Erik Reidar; Mork, Paul Jarle; Røe, Oluf Dimitri; Bauman, Adrian. (2018) The associations of sitting time and physical activity on total and site-specific cancer incidence: Results from the HUNT study, Norway. PLOS ONE
Vitenskapelig artikkel
Røe, Oluf Dimitri. (2018) Mesothelioma diagnosis and prognosis, are we moving beyond histology and performance status towards circulating biomarkers?. Journal of Thoracic Disease (JTD)
Leder
Markaki, Maria Dorothea Haaberg; Tsamardinos, Ioannis; Langhammer, Arnulf; Lagani, Vincenzo; Hveem, Kristian; Røe, Oluf Dimitri. (2018) A Validated Clinical Risk Prediction Model for Lung Cancer in Smokers of All Ages and Exposure Types: A HUNT Study. EBioMedicine
Vitenskapelig artikkel
Wang, Q; Chen, Q; Zhu, L; Chen, M; Xu, W; Panday, S. (2017) JWA regulates TRAIL-induced apoptosis via MARCH8-mediated DR4 ubiquitination in cisplatin-resistant gastric cancer cells. Oncogenesis
Vitenskapelig artikkel
Røe, Oluf Dimitri. (2017) The High Cost of New Cancer Therapies-A Challenge of Inequality for All Countries. JAMA Oncology
Short communication
Røe, Oluf Dimitri; Wahl, Sissel Gyrid Freim. (2017) The undifferentiated carcinoma that became a melanoma: Re-biopsy of a cancer of an unknown primary site: a case report. Journal of Medical Case Reports
Vitenskapelig artikkel
Li, Qiang; Zhi, Xiaofei; Zhou, Jianping; Tao, Ran; Zhang, Jiaxuan; Chen, Peisheng. (2016) Circulating tumor cells as a prognostic and predictive marker in gastrointestinal stromal tumors: A prospective study. OncoTarget
Vitenskapelig artikkel
Qian, Jing; Zhu, Weiyou; Wang, Keming; Ma, Lin; Xu, Jin; Xu, Tongpeng. (2016) JWA loss promotes cell migration and cytoskeletal rearrangement by affecting HER2 expression and identifies a high-risk subgroup of HER2-positive gastric carcinoma patients. OncoTarget
Vitenskapelig artikkel
Zhi, Xiaofei; Jiang, Baofei; Yu, Junbo; Røe, Oluf Dimitri; Qin, Jun; Ni, Qingfeng. (2016) Prognostic role of microscopically positive margins for primary gastrointestinal stromal tumors: a systematic review and meta-analysis. Scientific Reports
Vitenskapelig artikkel
Chen, Xiao-Feng; Qian, Jing; Pei, Dong; Zhou, Chen; Røe, Oluf Dimitri; Zhu, Fang. (2016) Prognostic value of perioperative leukocyte count in resectable gastric cancer. World Journal of Gastroenterology (WJG)
Vitenskapelig artikkel
Robles, Ana I.; Olsen, Karina Standahl; Tsui, Dana W.T.; Georgoulias, Vassilis; Creaney, Jenette; Dobra, Katalin. (2016) Excerpts from the 1st international NTNU symposium on current and future clinical biomarkers of cancer: innovation and implementation, June 16th and 17th 2016, Trondheim, Norway. Journal of Translational Medicine
Vitenskapelig artikkel
Røe, Oluf Dimitri; Panou, V. (2016) Pemetrexed as first or second line in 112 danish patients. Journal of Clinical Oncology
Sammendrag/abstract
Røe, Oluf Dimitri; Mjelle, Robin; Sætrom, Pål; Andreassen, Trygve; Bathen, Tone Frost; Hveem, Kristian. (2016) Serum microRNAs/enriched pathways in lung cancer 1-4 years before diagnosis: A pilot study from the HUNT Biobank, Norway. Journal of Clinical Oncology
Sammendrag/abstract
Qian, Jing; Qian, Yingying; Wang, Jian; Gu, Bing; Pei, Dong; He, Shaohua. (2016) A clinical prognostic scoring system for resectable gastric cancer to predict survival and benefit from paclitaxel- or oxaliplatin-based adjuvant chemotherapy. Drug Design, Development and Therapy
Vitenskapelig artikkel
Røe, Oluf Dimitri; Wyller, Torgeir Bruun. (2015) Hva står på spill med lokalsykehusene? :. Bioingeniøren
Leserinnlegg
Gao, Zhibin; Hiroshima, Kenzo; Wu, Xiaodong; Zhang, Jixian; Shao, Dichu; Shao, Huajiang. (2015) Asbestos textile production linked to malignant peritoneal and pleural mesothelioma in women: Analysis of 28 cases in Southeast China. American Journal of Industrial Medicine
Vitenskapelig artikkel
Zhu, Weiyou; Røe, Oluf Dimitri; Wu, Chen; Li, Wei; Guo, Renhua; Gu, Yanhong. (2015) Activity of pemetrexed-based regimen as first-line chemotherapy for advanced non-small cell lung cancer with asymptomatic inoperable brain metastasis: A retrospective study. Journal of chemotherapy
Vitenskapelig artikkel
Panou, V; Vyberg, M; Weinreich, UM; Meristoudis, C; Falkmer, UG; Røe, Oluf Dimitri. (2015) The established and future biomarkers of malignant pleural mesothelioma. Cancer Treatment Reviews
Vitenskapelig oversiktsartikkel/review
Røe, Oluf Dimitri; Stella, Giulia Maria. (2015) Malignant pleural mesothelioma: History, controversy and future of a manmade epidemic. European Respiratory Review
Vitenskapelig oversiktsartikkel/review
Røe, Oluf Dimitri. (2014) Postoperative leukopenia is an independent prognostic factor in resectable gastric cancer patients. Journal of Clinical Oncology
Sammendrag/abstract
Cao, Hailong; Zhou, Qing; Lan, Rongfang; Røe, Oluf Dimitri; Chen, Xin; Chen, Yijiang. (2014) A functional polymorphism C-509t in TGF-1 promoter contributes to susceptibility and prognosis of lone atrial fibrillation in chinese population. PLOS ONE
Vitenskapelig artikkel
Xu, W; Wang, S; Chen, Q; Zhang, Y; Ni, P; Wu, X. (2014) TXNL1-XRCC1 pathway regulates cisplatin-induced cell death and contributes to resistance in human gastric cancer. Cell Death & Disease
Vitenskapelig artikkel
Chen, Y; Huang, Y; Huang, Yulin; Xia, X; Zhang, J; Zhou, Y. (2014) JWA suppresses tumor angiogenesis via Sp1-activated matrix metalloproteinase-2 and its prognostic significance in human gastric cancer. Carcinogenesis
Vitenskapelig artikkel
Kerkentzes, Konstantinos; Lagani, Vincenzo; Tsamardinos, Ioannis; Vyberg, Mogens; Røe, Oluf Dimitri. (2014) Hidden treasures in "ancient" microarrays: Gene expression portrays biology and potential resistance pathways of major lung cancer subtypes and normal tissue. Frontiers in Oncology
Vitenskapelig artikkel
Chen, X; Zhu, Q; Liu, Y; Liu, P; Yin, Y; Guo, R. (2014) Icotinib is an active treatment of non-small-cell lung cancer: A retrospective study. PLOS ONE
Vitenskapelig artikkel
Xu, W; Chen, Q; Wang, Q; Sun, Y; Wang, S; Li, A. (2014) JWA reverses cisplatin resistance via the CK2-XRCC1 pathway in human gastric cancer cells. Cell Death & Disease
Vitenskapelig artikkel
Cao, Hailong; Zhu, Jinfu; Xi, Lei; Røe, Oluf Dimitri; Chen, Yijiang; Wang, Dongjin. (2014) Preoperative serum receptor activator of nuclear factor-κB ligand/osteoprotegerin predict stabilization of spontaneously restored sinus rhythm in persistent atrial fibrillation patients after mitral valve surgery. Cardiology
Vitenskapelig artikkel
Røe, Oluf Dimitri; Oppegaard, Per Arne; Revheim, Mona Elisabeth; Svindland, Aud. (2014) Adrenocortical carcinoma mimicking lung cancer and responding to vinorelbine/carboplatin and pemetrexed/carboplatin. BMJ Case Reports
Vitenskapelig artikkel
Cao, Hailong; Wu, Ying; Li, Qingguo; Wu, Yanhu; Zhou, Qing; Røe, Oluf Dimitri. (2014) Serum sRANKL/OPG predict recurrence after radiofrequency catheter ablation of lone atrial fibrillation. International Journal of Cardiology
Vitenskapelig artikkel
Huang, Yefei; Wang, Weimin; Chen, Yansu; Huang, Yulin; Zhang, Jianbing; He, Song. (2014) The opposite prognostic significance of nuclear and cytoplasmic p21 expression in resectable gastric cancer patients. Journal of gastroenterology
Vitenskapelig artikkel
Røe, Oluf Dimitri. (2014) Blodprøve kan avsløre lungekreft . Adresseavisen
Intervju tidsskrift
Røe, Oluf Dimitri. (2013) DNA repair suppression and effect of cisplatin in mesothelioma and lung cancer cell lines. Journal of Clinical Oncology
Sammendrag/abstract
Xi, Lei; Cao, HaiLong; Zhu, Jinfu; Røe, Oluf Dimitri; Li, Mingna; Wu, Yanhu. (2013) OPG/RANK/RANKL Axis in Stabilization of Spontaneously Restored Sinus Rhythm in Permanent Atrial Fibrillation Patients after Mitral Valve Surgery. Cardiology
Vitenskapelig artikkel
Chen, Yansu; Xia, Xiaowei; Wang, Shouyu; Wu, Xuming; Zhang, Jianbing; Zhou, Yan. (2013) High FAK combined with low JWA expression: clinical prognostic and predictive role for adjuvant fluorouracil-leucovorin-oxaliplatin treatment in resectable gastric cancer patients. Journal of gastroenterology
Vitenskapelig artikkel
Wang, Shouyu; Wu, Xuming; Zhang, Jianbing; Chen, Yansu; Xu, Jin; Xia, Xiaowei. (2013) CHIP functions as a novel suppressor of tumour angiogenesis with prognostic significance in human gastric cancer. Gut
Vitenskapelig artikkel
Cao, Hailong; Zhou, Qing; Wu, Yanhu; Li, Qingguo; Røe, Oluf Dimitri; Chen, Yijiang. (2013) Preoperative serum soluble receptor activator of nuclear factor-kappa B ligand and osteoprotegerin predict postoperative atrial fibrillation in patients undergoing cardiac valve surgery. Annals of Thoracic Surgery
Vitenskapelig artikkel
Cao, HaiLong; Li, Qingguo; Li, Mingna; Røe, Oluf Dimitri; Wu, Zhong; Zhou, Qing. (2013) Osteoprotegerin/RANK/RANKL axis and atrial remodeling in mitral valvular patients with atrial fibrillation. International Journal of Cardiology
Vitenskapelig artikkel
Ye, Yang; Li, Xuan; Yang, Jiangjing; Miao, Shuhan; Wang, Shouyu; Chen, Yansu. (2013) MDM2 is a useful prognostic biomarker for resectable gastric cancer. Cancer Science
Vitenskapelig artikkel
Chen, Xiaofeng; Liu, YQ; Røe, Oluf Dimitri; Qian, YY; Guo, RH; Zhu, LJ. (2013) Gefitinib or Erlotinib as Maintenance Therapy in Patients with Advanced Stage Non-Small Cell Lung Cancer: A Systematic Review. PLOS ONE
Vitenskapelig artikkel
Xu, CH; Wu, C; Xia, Y; Zhong, ZP; Liu, Xiang; Xu, Jing. (2013) WT1 Promotes Cell Proliferation in Non-Small Cell Lung Cancer Cell Lines Through Up-Regulating Cyclin D1 and p-pRb In Vitro and In Vivo. PLOS ONE
Vitenskapelig artikkel
Chen, Xiaofeng; Zha, Xiaoming; Chen, Wei; Zhu, Tingting; Qiu, Jinrong; Røe, Oluf Dimitri. (2013) Leptin attenuates the anti-estrogen effect of tamoxifen in breast cancer. Biomedicine & Pharmacotherapy
Vitenskapelig artikkel
Chen, Xiaofeng; Liu, YQ; Yin, YM; Jin, S; Ping, GQ; Røe, Oluf Dimitri. (2012) Recombinant human endostatin (endostar) decreased recurrent ascites, pleural fluid and ascitic VEGF in a case of advanced mesothelioma. Journal of chemotherapy
Vitenskapelig artikkel
Liu, Xin; Wang, Shouyu; Xia, Xiaowei; Chen, Yansu; Zhou, Yan; Wu, Xuming. (2012) Synergistic Role between p53 and JWA: Prognostic and Predictive Biomarkers in Gastric Cancer. PLOS ONE
Vitenskapelig artikkel
Tsamardinos, I; Borboudakis, G; Christodoulou, EG; Røe, Oluf Dimitri. (2012) Chemosensitivity Prediction of Tumours Based on Expression, miRNA, and Proteomics Data. International Journal of Systems Biology and Biomedical Technologies
Vitenskapelig artikkel
Røe, Oluf Dimitri; Szulkin, Adam; Anderssen, Endre; Flatberg, Arnar; Sandeck, Helmut; Amundsen, Tore. (2012) Molecular Resistance Fingerprint of Pemetrexed and Platinum in a Long-Term Survivor of Mesothelioma. PLOS ONE
Vitenskapelig artikkel
Chen, X.-F.; Wang, R; Yin, YM; Røe, Oluf Dimitri; Li, J; Zhu, LJ. (2012) The effect of monosialotetrahexosylganglioside (GM1) in prevention of oxaliplatin induced neurotoxicity: A retrospective study. Biomedicine & Pharmacotherapy
Vitenskapelig artikkel
Wang, SY; Wu, XM; Chen, YS; Zhang, JB; Ding, JJ; Zhou, Yan. (2012) Prognostic and Predictive Role of JWA and XRCC1 Expressions in Gastric Cancer. Clinical Cancer Research
Vitenskapelig artikkel
Cao, HaiLong; Wang, Jian; Xi, Lei; Røe, Oluf Dimitri; Chen, Yijiang; Wang, Dongjin. (2011) Dysregulated Atrial Gene Expression of Osteoprotegerin/Receptor Activator of Nuclear Factor-kappa B (RANK)/RANK Ligand Axis in the Development and Progression of Atrial Fibrillation. Circulation Journal
Vitenskapelig artikkel
Sandeck, Helmut; Røe, Oluf Dimitri; Kjærheim, Kristina; Willèn, Helena; Larsson, Erik. (2010) Re-evaluation of histological diagnoses of malignant mesothelioma by immunohistochemistry. Diagnostic Pathology
Vitenskapelig artikkel
Røe, Oluf Dimitri; Anderssen, Endre; Sandeck, Helmut; Christensen, Tone; Larsson, Erik; Lundgren, Steinar. (2010) Malignant pleural mesothelioma: Genome-wide expression patterns reflectinggeneral resistance mechanisms and a proposal of novel targets. Lung Cancer
Vitenskapelig artikkel
Røe, Oluf Dimitri; Anderssen, Endre; Helge, Eli; Pettersen, Caroline Hild; Olsen, Karina Standahl; Sandeck, H. (2009) Genome-Wide Profile of Pleural Mesothelioma versus Parietal and Visceral Pleura: The emerging Gene Portrait of the Mesothelioma Phenotype. PLOS ONE
Vitenskapelig artikkel
Røe, Oluf Dimitri; Creaney, J; Lundgren, Steinar; Larsson, Erik; Sandech, Helmut; Boffetta, P. (2008) Mesothelin-related Predictive and Prognostic Factors in Malignant Mesothelioma, a nested case-control study. Lung Cancer
Vitenskapelig artikkel
Kjaerheim, K; Røe, Oluf Dimitri; Waterboer, T; Sehr, P; Rizk, R; Dai, HY. (2007) Absence of SV40 antibodies or DNA fragments in prediagnostic mesothelioma serum samples. International Journal of Cancer
Vitenskapelig artikkel

Rapport

Røe, Oluf Dimitri. (2008) Malignant Mesothelioma:Virus, Biomarkers and Genes- a Translational Approach. NTNU/Oluf Dimitri Røe
Doktorgradsavhandling

PRODUKT

Kleppen, Dag Mattis; Pavlovic, Jovan; Fossen, Anne; Azziz, Idd; Røe, Oluf Dimitri; Haug, Christian. (2010) Bengalo : Foy.
Musikk - innspillingsprodukt

Undervisning

Emner

MOL8001 - Molecular Physiology: Mechanisms and Methods

Formidling

2016

Intervju

Røe, Oluf Dimitri. (2016) Studieresultater fra HUNT kan gi tidlig lungekreft-svar. Trønder-avisa Trønder-avisa [Internett] 2016-06-10

2013

Poster

Røe, Oluf Dimitri; Chen, Duan; Chen, Wu; Chen, Yijiang; Zhi, Xiaofei. (2013) DNA repair suppression and effect of cisplatin in mesothelioma and lung cancer cell lines. ASCO ASCO 2013 , Chicago 2013-05-30 - 2013-06-03

2012

Poster

Røe, Oluf Dimitri. (2012) Cell cycle checkpoint genes and homologous recombinational repair are overexpressed in malignant pleural mesothelioma. International Mesothelioma Interest Group IMIG 2012 , Boston 2012-09-11 - 2012-09-14
Vitenskapelig foredrag

Røe, Oluf Dimitri. (2012) MicroRNA in Cancer. School of Public Health Nanjing Medical University , Nanjing Medical University 2012-12-15 - 2012-12-15
Poster

Røe, Oluf Dimitri. (2012) Comparative evaluation of Affymetrix and Illumina genome-wide expression data in Pleural Mesothelioma. HSCBB 7th conference of the Hellenic Society for Computational Biology & Bioinformatics - HSCBB12 FORTH, Heraklion, Crete, , Heraklion 2012-10-04 - 2012-10-06
Vitenskapelig foredrag

Røe, Oluf Dimitri. (2012) Fanconi anemia genes, RHINO and other cell cycle checkpoint genes are overexpressed in malignant pleural mesothelioma. IKMM, NTNU The 3rd Erling Seeberg symposium, June 2012 in Trondheim and Ørland, Norway , Ørland 2012-06-19 - 2012-06-24
Poster

Røe, Oluf Dimitri. (2012) Differentially expressed genes of major lung tumour subtypes and normal lung tissue. HSCBB Proceedings of the 7th conference of the Hellenic Society for Computational Biology & Bioinformatics - HSCBB12 FORTH, Heraklion, , Heraklion 2012-10-04 - 2012-10-06
Poster

Røe, Oluf Dimitri. (2012) Mesothelioma cluster in a medium sized hospital in South-East China: Relations to asbestos exposure and clinicopathological findings. International Mesothelioma Interest Group IMIG 2012 , Boston 2012-09-11 - 2012-09-14

2011

Poster

Røe, Oluf Dimitri. (2011) Information-Preserving Techniques Improve Chemosensitivity Prediction of Tumours Based on Expression Profiles. Engineering Applications of Neural Networks-EANN Engineering Applications of Neural Networks - 12th INNS EANN-SIG International Conference, EANN 2011 and 7th IFIP WG 12.5 International Conference, AIAI 2011 , Corfu 2011-09-12 - 2011-09-18

2006

Poster

Røe, Oluf Dimitri; Andersen, Endre; Helge, Eli; Standahl-Olsen, Karina; Larsson, Erik; Lundgren, Steinar. (2006) Microarray of normal mesothelium and mesothelioma-visceral and parietal pleura has distinct gene expression profile-consequences for oncogenesis of mesothelioma?. 8th International Conference of the International Mesothelioma Interest Group , Chicago, Illinois 2006-10-19 - 2006-10-22

2005

Poster

Røe, Oluf D; Creaney, J; Lundgren, Steinar; Larsson, Erik; Sandech, H; Bofetta, P. (2005) SMRP (Soluble Mesothelin Related Protein), CYFRA 21-1 and CA125 in serum 1-30 years before mesothelioma diagnosis: a case-control study. The International Mesothelioma Symposium 2005-11-22 - 2005-11-27

Språkvelger

Oluf Dimitri Røe